Summary – In this episode of Monetizing Innovation, we sit down with Ross Youngs, CEO and Founder of Biosortia, to explore a breakthrough at the intersection of microbiomes, AI-driven discovery, and scalable innovation.
Ross shares how Biosortia is unlocking previously unobtainable, drug-like small molecules directly from microbiomes—transforming how therapeutics, agrochemicals, longevity science, and life sciences approach discovery and de-risking.
We discuss why scale is the real innovation advantage, how accessing the “hidden chemistry of life” changes the economics of drug discovery by orders of magnitude, and what it takes to turn deep science into partner-ready IP with complete AI datasets.
A must-listen for founders, investors, and innovation leaders navigating the future of biotech, AI, and monetizable science.
Summary – In this powerful and reflective episode, Ross shares how his journey through biology, genetics, engineering, and leadership has come full circle with purpose. Drawing from science, nature, and lived experience, Ross explores why strong, grounded male leadership still matters, the importance of mentorship and psychological safety, and how every phase of life prepares us for the work we’re meant to do. This conversation is a reminder that real progress—whether in innovation or leadership comes from balance, courage, and learning from those who have walked the path before us.
Summary – The pharmaceutical industry is currently trapped by two opposing forces—the saturation of common natural scaffolds and the infinite dilution of synthetic libraries—which collectively drive Eroom’s Law and push the cost of discovery to unsustainable levels. Our strategy reverses this trend by deploying a hybrid model that mines the “dark matter of biology”—the vast, unexplored chemical grammars hidden in rare biomes—to serve as the structural priors for AI-driven design. By decoding these evolutionary rules first, we effectively bypass the high failure rates of random synthetic screening, ensuring that our earliest preclinical candidates already possess the “bilingual” capacity to satisfy both therapeutic targets and biological safety constraints. This approach front loads value creation, shifting the investment opportunity to the earliest preclinical stage where the de risking occurs, thereby securing the highest possible ROI as envisioned by our Proof of Concept WL-Portfolio asset.
Summary –
Discussed in this Podcast
→ How microbiome mining could cure cancer, Alzheimer’s & more
→ Processing 2 MILLION liters of water daily to extract microbes
→ Accessing drug-like molecules that evolution perfected over 3.4 billion years
→ Why this could be worth TRILLIONS in the next 25 years
→ Transforming agriculture, cosmetics & environmental remediation
KEY TAKEAWAY: “Microbes have always been chemical researchers and factories of life. Biosortia’s breakthrough technology now effectively opens the door to ALL microbes.” – Ross Youngs
This technology could literally transform how we discover new medicines and accelerate first-in human trials globally!
Summary – Ross has developed proprietary technology to mine microbiomes, already discovering 110,000+ novel small molecules with potential applications across pharmaceuticals, agriculture, and beyond.
Why investors should tune in:
– First-mover advantage in an untapped market
– Technology validated by Los Alamos National Lab
– Platform business model with multiple revenue streams
– Potential to generate 4X the human knowledge on microbial molecules annually
Ross brings exceptional credentials as a serial entrepreneur who’s built Inc. 500 companies and secured backing from DARPA, NIH, and major research institutions.
Summary – Join us for an inspiring episode of Mastering the Numbers as host Joe Mallo sits down with Ross Youngs, the visionary founder and CEO of Biosortia. In this in-depth conversation, Ross shares his journey of groundbreaking innovation, from his early days in plastics manufacturing to revolutionizing drug discovery. Learn how Biosortia is leveraging advanced technology and natural resources to access molecules that could transform medicine, agriculture, and cosmetics. Ross also dives into the challenges of scaling a startup, the importance of partnerships, and how perseverance led to game-changing advancements in their mission to serve the world’s most critical needs. Discover how Biosortia is breaking barriers by unlocking 100% of nature’s molecular secrets, a feat supported by top institutions like DARPA, ARPA-E, and Los Alamos National Lab. Ross discusses the potential of their technology to reduce pharmaceutical costs, foster global health innovation, and fuel competition in critical markets. This is a must-watch for entrepreneurs, scientists, and anyone curious about the future of biotechnology.
Summary – Discover the immense, untapped power of nature through groundbreaking Industrial Scale Microbiome Mining. While microbes have shaped the planet and all life, their interactions with humans extend far beyond infectious disease. The microbial world remains a vast, underexplored reservoir of molecules with extraordinary potential.
Summary – The new mining toolbox will start slow worldwide, but as the pipelines fill with new opportunities, microbial access facilitates adoption, and technology advances will accelerate. It is likely, in short order, 3-5 years, that new opportunities in therapeutics will impact rare and orphan diseases. Other life science areas will also benefit, including agrochemicals, sustainability, remediation, carbon capture, advanced energy, and cosmetics. Within ten years of execution and widespread adoption, most pipelines will be traced to the opportunity of untapped microbes of the earth.”- Ross Youngs
Summary – Explore groundbreaking biotechnology advancements with Ross, an inventor with 75 patents. Discover how his work is unlocking nature’s hidden molecules and revolutionizing the health and technology sectors.
