Natural Products Driven Medicinal Chemistry

December 4, 2024 | By Sandip B. Bharate* and Craig W. Lindsley*

Natural products (NPs) have historically served as the basis for a variety of therapeutic applications including treatments in the fields of oncology, infectious diseases, and central nervous system (CNS) disorders. In this cross-journal thematic Virtual Special Issue, we feature contributions from the Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, ACS Bio & Med Chem Au, the Journal of Natural Products, ACS Chemical Neuroscience, and ACS Chemical Biology. You will find a wide range of topics covered including the isolation of compounds, medicinal chemistry lead optimization, and virtual screening of natural product libraries. We hope our readers will enjoy this collection of manuscripts aimed to provide a better understanding of how natural product scaffolds can be used in drug discovery.