- by sedlv
- July 17, 2023
DTx Pharma announces acquisition by Novartis
(July 17, 2023) | By Christina Trout – DTx Pharma.
- DTx Pharma’s Fatty Acid Ligand Conjugated Oligonucleotide (FALCON™) platform facilitates extra-hepatic delivery of siRNA therapeutics
- Acquisition includes DTx-1252 with the potential to deliver a transformative medicine to Charcot-Marie-Tooth Disease Type 1A (CMT1A) patients
- Acquisition also includes additional early-stage programs in neuromuscular and CNS indications
- Novartis will make an upfront payment of $500M and additional payments of up to $500M upon completion of pre-specified milestones
SAN DIEGO, July 17, 2023 /PRNewswire/ — DTx Pharma, a preclinical stage biotechnology company addressing the delivery challenges of oligonucleotide therapeutics with its Fatty Acid Ligand Conjugated OligoNucleotide (FALCON™) platform, announced today that it has been acquired by Novartis. The FALCON platform enables the delivery and activity of small interfering RNA (siRNA) therapeutics to tissues beyond the liver, enhancing biodistribution and cellular uptake. DTx Pharma’s lead program is currently in preclinical development, with FDA Orphan Drug Designation, for the treatment of Charcot-Marie-Tooth Disease Type 1A (CMT1A). CMT1A is a progressive, neuromuscular, autosomal-dominant disease that can lead to life-long loss of muscle function and disability.